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PGC-1 alpha expression decreases in the Alzheimer diasease brain as a function of dementia

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Ursolic acid induces mitochondrial biogenesis through the activation of AMPK and PGC-1 in C2C12 myotubes: a possible mechanism underlying its beneficial effect on exercise endurance

The tetrameric form has an interaction with ankyrin that forms a macrocomplex which anchors the membrane to the underlying cytoskeleton, a critical activity for both structural support and functional gas exchange