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Once outside the cell, glutathione (GSH) degradation occurs exclusively in the extracellular space, and only on the surface of cells that express the ectoenzyme -glutamyl transferase

[DOI] [PMC free article] [PubMed] [Google Scholar] Foyer C.H., Noctor G

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MSH binding sites seem to be widely distributed throughout the central nervous system

The challenges of responding to this pandemic have been attributed to a myriad of factors including incomplete knowledge of SARS-CoV-2 pathophysiology, the mechanisms of action by which it causes harm, and the immune responses of individuals with comorbidities