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Likewise, the mitochondrial complex III activity is reduced significantly in the ischemia/reperfusion rabbit model, which is associated with elevated ROS levels [123]

Studies have found that it interacts with other cell death pathways such as apoptosis, necrosis, and pyroptosis ( At present, drug development for ferroptosis is still in its infancy, and the development of targeted drugs is progressing slowly

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Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology