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Therefore, studying and understanding methods that can target intestinal tight junction proteins to protect or restore barrier function is crucial for the development of therapeutic options
A general finding is that obese patients fulfilling criteria for MetS together with low IGF-1 plasma levels tend to develop a worse cardiovascular disease outcome than those with mid-normal to high-normal IGF-1 levels [213]
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All data are entered twice by two different data operators within 1 week of data collection
5c and Supplementary Figs
