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Additional research has also demonstrated that professional carnitine administration can be used to lower clinically high blood pressure levels, treat congestive heart failure, manage cardiac ischemia (the restriction of blood flow to the heart), and peripheral arterial diseases, a condition characterized primarily by poor circulation in the legs (known as intermittent claudication)

[DOI] [PubMed] [Google Scholar] 85.Schols L, Zange J, Abele M, Schillings M, Skipka G, Kuntz-Hehner S, van Beekvelt MC, Colier WN, Muller K, Klockgether T, Przuntek H, Vorgerd M

Propionylcarnitine possesses three characteristics that distinguish this acylcarnitine from other members of the carnitine pool

Polyol pathway hyperactivity is closely related to carnitine deficiency in the pathogenesis of diabetic neuropathy of streptozotocin-diabetic rats J Pharmacol Exp Ther 1998

Renal impairment, worsening renal function, and outcome in patients with heart failure: an updated meta-analysis