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The reaction itself, even when severe, typically does not necessitate cessation of therapy

Additionally, saliva possesses antioxidant capacity, which helps neutralize free radicals

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The ratio of GSH/GSSG was significantly decreased in CuO2 treated groups

It has become clear that vitamin D deficiency needs to be corrected at multiple levels: (i) vitamin D supplements and/or vitamin D-rich foods need to be consumed to provide adequate vitamin D, (ii) the body needs to be able to upregulate vitamin D-metabolizing genes to convert vitamin D into 25(OH)VD and then to 1,25(OH) 2 VD, and (iii) the levels of inflammatory biomarkers need to be reduced