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Savastano S, Di C, Barrea L, Colao A

Section 1886(d)(5)(K)(ii)(I) of the Act specifies that a new medical service or technology may be considered for new technology add-on payment if, based on the estimated costs incurred with respect to discharges involving such service or technology, the DRG prospective payment rate otherwise applicable to such discharges under this subsection is inadequate

Due to its insolubility, intratubular deposition of crystals occurs, obstructing the nephron, causing resistance to renal blood flow, and leading to the accumulation of creatinine, uric acid, and urea