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doi: 10.1001/jamanetworkopen.2022.38804 187 Fernndez-de-Las-PeasCNotarteKIPeligroPJVelascoJVOcampoMJHenryBMet al

NON-CANONICAL REGULATORY FUNCTIONS OF METABOLIC ENZYMES IN HCC In recent years, accumulating evidence has revealed that metabolic enzymes in HCC exhibit dual functionalities: not only do they sustain tumor growth through their canonical catalytic activities, they also exert diverse non-enzymatic functions that contribute significantly to oncogenesis [82-84]

In contrast, combining JKE-1674 and bezafibrate treatment significantly suppressed tumor growth within the peritoneal cavity (Supplementary Fig

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Transl Psychiatry (2013) 3:e220.10.1038/tp.2012.143 29 NovarinoGEl-FishawyPKayseriliHMeguidNAScottEMSchrothJet alMutations in BCKD-kinase lead to a potentially treatable form of autism with epilepsy