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Problems can also arise after intestinal or stomach surgeries are performed

There is no robust body of randomized controlled trial data demonstrating that lipotropic injections cause clinically significant fat loss beyond what the accompanying calorie restriction, activity changes, and clinical monitoring would have produced anyway

An average weight loss of -8.1 kg and -10.2 kg was attained at the end of 56 weeks with phentermine 75 mg plus topiramate 460 mg, and phentermine 150 mg plus topiramate 920 mg, respectively

Attributed to enhanced VEGF secretion and reduced oxidative stress markers