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This has been demonstrated with the 5-HT 4 agonist, prucalopride, which modified responses of T2helper cells and shortened post-operative ileus (Matteoli et al., 2013

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This dual-agonist strategy leverages complementary mechanisms: Cagrilintides amylin receptor activity pairs with semaglutides GLP-1 receptor agonism to produce additive or synergistic weight loss and metabolic benefits

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