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8,2022 The mechanism behind this interesting finding appears to be ethanols competitive utilization of the CYP 2E1 substrate, which diminishes the NAPQI byproduct of phase I APAP metabolism

OFlaherty, C

doi: 10.1128/JVI.00694-10, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 149.Carrasco-Hernandez R, Jacome R, Lopez Vidal Y, Ponce de Leon S

leucine, isoleucine, valine), alanine, glutamine, threonine, tyrosine, arginine, ornithine, glycine, methionine, and proline typically lower in the luteal phase compared to follicular and menstrual phases [3,138]

Supplementing with a bioavailable form is a common way to bridge that gap.
