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Unlike full HGH, AOD-9604 does not stimulate IGF-1 production or general growth pathways

However, their poor cell permeability has limited their use

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Through SASP, senescent cells may permanently confer a state of stemness in neighboring cells and thereby impair tissue function and renewal, an effect which we recently described in the senescence-stem lock model for aging (de Keizer, 2017)

BPC-157 is a 15-residue pentadecapeptide sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) derived from a partial sequence of gastric juice protein