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Nat Rev Immunol 5:331342

GH excess is much rarer than GH deficiency in childhood and can be caused by pituitary adenomas, optic nerve gliomas (seen predominantly with NF1), McCune Albright syndrome, or Carney complex
Sibarov et al
This demonstrates that KDs neuroprotective effects are at least partly mediated by its influence on the gut microbiota rather than by direct metabolic effects alone