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(2015) 10:e0134311

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The Cochrane database of systematic reviews , (12), CD007769

Its a very limited study and I dont know how accurate it was, I assume that the b12 wasnt the little vials that we use today hence the smaller amounts injected in the study

241 A phase 1/2 (ECHO-202/KEYNOTE-037) trial evaluating the effectiveness of the IDO1 inhibitor epacadostat combined with pembrolizumab on advanced solid tumors showed a high objective response rate (ORR) of 40.3% overall and 61.9% in malignant melanoma patients, demonstrating promising antitumor efficacy