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The potential synergy between cancer vaccines and chemotherapy results from certain chemotherapeutic agents triggering immunogenic cell death, making dying cancer cells more recognizable to the immune system, which may enhance the effectiveness of cancer vaccines (Obeid et al., 2007)

In this case, the local clock determines when a tissue is more or less sensitive to respond to hormonal stimulation

(2020) discovered artesunate inhibited the growth of cultured Merkel cell polyomavirus (MCPyV)-positive MCC cell lines effectively, and artesunate-induced cell death in investigated MCC cell lines can be significantly reduced by ferrostatin-1, deferoxamine and rosiglitazone (an inhibitor of the ACSL4)

this kind of GPXs are shown to be reduced by redoxins, namely, thioredoxins or related proteins with a CXXC motif in plants, yeast, insects and protists 15,17

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