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By delivering powerful nutrients directly into the bloodstream, IV therapy speeds up healing and prevents future outbreaks. Additionally, this targeted approach ensures your body has the right tools to keep cold sores at bay and improve quality of life. When To Consider IV Therapy You may want to consider IV therapy if you experience frequent cold sore outbreaks, especially during times of stress or when your immune system is weakened. However, before you get IV therapy, make sure you consult with a healthcare provider