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Description
The literature reveals that Nrf2 plays a role in the development and progression of gliomas with isocitrate dehydrogenase mutations, further confirming an interplay between oxidative stress and isocitrate dehydrogenase mutations [26]

Any receptor that is stimulated continuously tends to become less responsive over time it down-regulates

doi: 10.1074/jbc.M707528200

Carpenter DJ

Endocrinology Focus : Designed for research use only, not for human consumption
