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The NHS symptoms list groups them into general anaemia symptoms (tiredness, breathlessness, headaches, loss of appetite, weight loss) and neurological signs (peripheral neuropathy, balance problems, depression, memory and concentration changes, sometimes mood changes or psychosis in advanced cases)

Higher purity generally indicates that fewer unwanted compounds are present in the sample, although researchers should evaluate purity alongside other quality metrics

Vitamin B12 was negatively correlated only with body mass index

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Contributing factors may include the patients literacy level, financial resources, lack of health insurance, patients daily schedule, presence or absence of family support, learning disabilities, or neurologic deficits or conditions