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Collectively, these studies indicate that modulation of NAD + levels affects additional critical cellular pathways other than mitochondrial homeostasis

Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model
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The maintenance dose is generally 1500mcg once a month, or at a schedule determined by the physician based on the patient's ongoing clinical needs and blood test results

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