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Adding further complexity, regional heterogeneity in microglial phenotypes, such as differences between striatal and cortical microglia in PD, can influence treatment responses and must be carefully considered in the design of targeted therapies

Alistipes indistinctus-derived hippuric acid promotes intestinal urate excretion to alleviate hyperuricemia

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doi: 10.1038/s41430-021-00914-5
