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Additionally, the increased levels of citrate in the cytoplasm activate the key regulatory enzyme of fatty acid biosynthesis, acetyl-CoA carboxylase (ACC) while at the same time citrate allosterically inhibits the rate-limiting enzyme of glycolysis, PFK-1

Protective effects of anethole dithiolethione against oxidative stress-induced cytotoxicity in human Jurkat T cells

10.1021/nn501640q 90 TangP

In addition, certain proteins are particularly susceptible to forming adducts with acetaldehyde
