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For example, you shouldn't use this medication if you're allergic to cyanocobalamin or cobalt, or if you have Lebers disease, which is an inherited form of vision loss

In this sense, Rosenbloom, et al

Benjamini Y, Hochberg Y: Controlling the false discovery rate: a practical and powerful approach to multiple testing

Reported plasma levels of phenformin after 50-100 mg of phenformin uptake in patients are ~1.7 M 67 , while tissue concentrations have not been assessed but are expected to be much higher as reported in animal models 68