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HIF-1, Hypoxia-inducible factor 1 alpha

[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Li X.Y., Hou H.T., Chen H.X., Liu X.C., Wang J., Yang Q., He G.W

Since these findings proposed an interrelationship between oxidative stress and GN-induced ARF, we investigated this hypothesis in our study revealing that oxidative stress was linked to the induction of ARF in rats using GN, as evidenced by elevated renal MDA levels and decreased levels of nitrite and SOD

In particular, nano-formulation strategiesincluding polymeric nanoparticles, lipid-based nanocarriers, nanoemulsions, and micellar systemshave shown promise in improving solubility, stability, and pharmacokinetic behavior

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