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A candidate for a potential glutathione-scaffold residue was identified using the following selection criteria: The residue should be rather conserved in enzymatically active in contrast to inactive glutaredoxins and have a charged side chain to ensure a strong ionic glutathione interaction (Fig

The immunomodulatory effects of Carapax trionycis ultrafine powder on cyclophosphamide-induced immunosuppression in Balb/c mice

S., Salehi, A., Holm, C

However, there is a small subset of patients that does not obey this pattern, displaying median expression of NRF2 and low expression of KEAP1 red dots (NRF2-KEAP1 alteration) indicating a higher activity of the transcription factor in those tumors

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