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After verifying ANOVA assumptions, two-way ANOVA was then used to assess for a sex by genotype interaction and main effects

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MTR or MS) or betaine-homocysteine methyltransferase (BHMT) to complete the methionine cycle (Figure 2) [15]

The pathogenic mechanisms by which BBB breakdown leads to neuronal injury, synaptic dysfunction, loss of neuronal connectivity and neurodegeneration are described

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