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Clinical trials have demonstrated substantial reductions in hemoglobin A1c levels (up to 2.5% reduction) in type 2 diabetes, while weight management trials showed 15-21% weight loss in adults with obesity without diabetes

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Payer contracts add another layer of variation on top of that

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J Clin Invest 115:6675

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B12 deficiency can lead to symptoms such as fatigue, weakness, shortness of breath, cognitive changes, peripheral neuropathy (pins and needles), and anaemia

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Estradiol levels, hematocrit, PSA, and DHT MUST be monitored and controlled carefully with injection therapy

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