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However, the signaling mechanisms and the networks changes determining how attention mechanisms are pathological and how they are recruited in tinnitus remain unclear

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PMID: 238 ParamashivanB.ThamaraiR.SubramaniamK.KamarajC.Al-GhanimK

[DOI] [PubMed] [Google Scholar] 149.Fatima A., Rahul, Siddique Y.H

This conclusion is further supported by the observation that mice lacking Epac1 , which encodes one of the two isoforms of EPAC in mammals, are more resistant to DIO and have improved glucose tolerance and heightened central leptin sensitivity, as measured through STAT3 activation, compared with control mice 98