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Description
This protective response involves up-regulations of the GSH-synthesizing enzyme, GSH-synthetase, the GSH-conjugating enzyme, GST, and the hepatocellular efflux pumps, Mrp2 and Mrp1

J., vol

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Allergology international : official journal of the Japanese Society of Allergology 68(3):301308

8 In general, GADs enzymatic activity is thought to be regulated through two processes: 1) the level of enzyme expression, and 2) the degree of association with its cofactor pyridoxal phosphate (PLP)