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Lancet Glob Health 5(12):e1221e1234 Das S et al (2022) Innate immunity dysregulation in aging eye and therapeutic interventions

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The widely repeated claim that Dihexa is "seven orders of magnitude more potent than BDNF" originates from that flagged McCoy paper and reflects an assay-specific in-vitro spine-density measurement picomolar Dihexa versus nanomolar BDNF in one assay not a millions-fold advantage in a living brain