glutathione bronchiectasis S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility? Bronchiectasis management in adults: state

Characterization of the DosR regulon in mycobacteria and related actinomycetes has identified a set of common core genes encoding universal stress proteins, -crystallin chaperones, nitroreductase-domain proteins, triacylglyceride synthases, and YfiA-like hibernation factors that are presumed to facilitate transition to a survival phenotype, together with a set of peripheral genes with restricted distribution (Gerasimova et al., 2011)

AKR1C2 (type 3 3-HSD/bile acid binding protein) reduces the potent androgen, 5-dihydrotestosterone (5-DHT) to the weak androgen 3-androstanediol and prevents the binding of androgen to the androgen receptor

doi: 10.1016/S0079-6123(08)81008-4 42 KalluriRLeBleuVS

May 24 2017;57(8):1749-1758

Administering hepsin to wild-type mice increases APAP tolerance and downregulates GJ expression Considering the potential clinical and medical applications, we evaluated a therapeutic strategy involving the administration of hepsin to wild-type adult mice and assessed its potential to mitigate APAP-induced liver injury