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In psoriasis, increased levels of MDA and 4-HNE have been consistently observed in lesional skin, correlating with disease severity and PASI score
Amadio M, Govoni S, Pascale A (2016) Targeting VEGF in eye neovascularization: Whats new?: A comprehensive review on current therapies and oligonucleotide-based interventions under development

It plays a critical role in protecting cells from oxidative stress, detoxifying the body, and supporting immune function