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It seems prudent not to use valproate sodium in patients with acute head trauma for the prophylaxis of post-traumatic seizures until further information is available
In humans, -KG has been demonstrated to have therapeutic potential in conditions affecting the heart, brain, liver, and skeletal muscles, and may also influence human aging [125]
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This in turn leads to redistribution of the lipophilic drug from the target tissues into the blood, lowering drug concentration in the target tissues
