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Mechanistically, these effects stem from phytoestrogens weak selective estrogen receptor modulator (SERM) activity, preferentially binding ER and influencing estrogen-responsive genes, particularly in estrogen-dominant phases (follicular/ovulatory)
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Prolonged ventricular perfusion with H 2 S donor NaHS attenuates Ang II-induced increase and activation of paraventricular nuclear astrocytes and alleviates Ang II-dependent autonomic dysfunction [176]
American Association of Clinical Endocrinology Consensus Statement: Algorithm for Management of Adults With Type 2 Diabetes 2026 Update
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