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Doxorubicin is an anti-cancer reagent that is metabolized into inactive doxorubicinol by CYP2D6 and CYP3A4 (Fig

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Similarly, dissolution allicin release from non-enteric Kwai (Lichtwer Pharma, Berlin) tablets, the most commonly used garlic supplement in cardiovascular clinical trials [1,2], has also been found to be problematic: 44% for tablets made before 1993 and only 15% for tablets made from 19941997 [31]