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[DOI] [Google Scholar] 19.Panou A., Karabagias I.K

About the Experts: Lester Lee, M.D., is a regenerative medicine physician specializing in hormone replacement therapy

Several pathways have been found by which ROS promotes damage and disassembly of meiotic spindle microtubules in oocytes ( 64 ): Stability of the spindle is dependent on maintaining the dynamic equilibrium between polymerization (assembly) and depolymerization (disassembly) of tubulin subunits to maintain intact spindle microtubules