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Description
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Clinical severity was graded as 0 (normal), 0.5 (erythema and edema in only one digit), 1 (erythema and mild edema of the footpad, or ankle or two to five digits), 2 (erythema and moderate edema of two joints [footpad or ankle, two to five digits]), 3 (erythema and severe edema of the entire paw), or 4 (reduced swelling and deformation leading to incapacitated limb) 68

A contamination focused approach for optimizing the single-cell RNA-seq experiment
Reconstitution mistakes

220,221,222 Emerging evidence indicates that copper and copper-based compounds play a role in the activation of necroptosis (Fig