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Reactive oxygen species can oxidize and directly enhance CaMKII activity, which in turn phosphorylates and activates several Ca 2+ -handling proteins such as the cardiac ryanodine receptor RyR2 or cardiac SERCA ( Protein O-linked-N-acetylglucosaminylation (O-GlcNAcylation) plays important roles in calcium handling under diabetic conditions (Figure 2)

The ubiquitin-proteasome and autophagy pathways are vital to the cells ability to maintain the delicate balance between the production and degradation of proteins and cellular components

Vitreoretinal surgeons have recently made improvements to vitrectomies to make these retinal tears less likely

We believe that proper measurement is a cornerstone of good science

doi: 10.1007/s12264-017-0134-1