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The active site of MGST1 might thus benefit from membrane proximity and/or a xenobiotic substrate gradient extending into the cytosol (as hydrophobic molecules are concentrated in the membrane)
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doi: 10.1016/j.ijbiomac.2020.05.163
The side effect and safety profile were like those observed with GLP-1 receptor agonists and GIP/GLP-1 receptor co-agonists with mild to moderate gastrointestinal events occurring mostly during dose escalations [64]
