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19, 10401043.10.1203/00006450-198504000-00717 88 LimC

Sahli MW, Mares JA, Meyers KJ, Klein R, Brady WE, Klein BE, et al

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For immunohistochemistry, deparaffinized sections were immunolabeled using antibodies for anti-GPX4 (ab125066, Abcam), anti-4HNE (HNEJ-2, JaICA), anti-KIM-1 (AF1817, R&D) and anti-cleaved caspase-3 (9661, Cell Signaling)

Effects of Ac-G combined pre-treatments on the cellular antioxidant defense network response against oxidative stress During oxidative stress, the endogenous antioxidative system (antioxidant enzymes and GSH) is overwhelmed by high free radicals and ROS levels, leading to oxidative damage to cellular structures, including membrane lipids (32)