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This GSH redox cycle takes place in the cytosol and mitochondria, whereas GSH is compartmentalized in mitochondria [38], the major intracellular source of ROS [39], after its synthesis in cytosol

Poole, L.B

233 Peptidylarginine deiminase 4 (PAD4) can regulate arginine methylation and gene expression by removing methyl groups from H3R2, H3R8, H3R17, and H3R26, and then converting arginine to citrulline

2016;13(10):e1002152

4-hydroxy-2(E)-Nonenal Facilitates NMDA-Induced Neurotoxicity via Triggering Mitochondrial Permeability Transition Pore Opening and Mitochondrial Calcium Overload
