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Ursodeoxycholic acid (UDCA) has been found ineffective for pruritus relief in primary sclerosing cholangitis and primary biliary cholangitis but is recommended for treating pruritus in intrahepatic cholestasis of pregnancy only, at doses of 1015 mg/kg/day, divided into 23 doses

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Lipopeptides target both the appearance and the cause of wrinkles: Stimulating cell renewal : they activate the skins natural repair mechanisms

Route of administration also affects observed half-life