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Tao L, Yang X, Ge C, Zhang P, He W, Xu X, Li X, Chen W, Yu Y, Zhang H, et al

Upregulated Hexokinase 2 expression induces the apoptosis of dopaminergic neurons by promoting lactate production in Parkinsons disease

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That DeepMet recapitulated the existence of metabolites that were not captured in existing maps of the metabolome underscores its ability to fill the gaps in these maps, and raises the possibility that DeepMet could facilitate artificial intelligence-guided curation efforts to more comprehensively catalogue the known metabolome

In mammals, three isoforms of SOD (SOD1, SOD2, SOD3) exist, and all require a redox active transition metal in the active site to accomplish the catalytic breakdown of the superoxide anion (82, 385)