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In a recent study, curcumin, demethoxycurcumin, and bisdemethoxycurcumin significantly attenuated the production of pro-inflammatory cytokines in a MCD diet-induced NAFLD mouse model

Pathogen killing is initiated by the assembly of the superoxide (O 2 )-generating NADPH oxidase complex at the phagosomal membrane for the production of reactive oxygen/nitrogen species (ROS/RNS) and concomitant delivery of the heme enzyme myeloperoxidase (MPO) and other antimicrobial enzymes into the phagosome
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