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Second, aged-rat natural cognitive decline used in McCoy 2013 to test Dihexa in a non-pharmacological cognitive-impairment model

Conversely, a single measure of objective sleep (even if an adaptation night or an average of several nights is used) may also be an imperfect estimate of how an individual typically sleeps

In vivo studies demonstrated pronounced analgesic activity, evidenced by significant reduction in nociceptive responses in classic rodent pain models (formalin-induced paw flinch, tail-flick)

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