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Abstract Purpose of Review Provide an overview of the expanding landscape of mast cell (MC)targeting treatments in mast cell activation syndromes (MCAS)
Normal and expected reactions include a brief stinging or burning sensation during or immediately after injection, mild redness or warmth at the injection site lasting a few minutes, and small temporary lumps that resolve within 30 to 60 minutes as the solution disperses through subcutaneous tissue
Although further multi-omics studies will certainly uncover more specific epigenetic profiles, a comprehensive genome-wide overview cannot be completed without in-depth functional analyses to reveal pathogenic mechanisms at the molecular level
