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While certain studies indicate elevated central glutathione levels with intravenous or high-dose oral NAC, others do not replicate these results, particularly in clinically relevant brain areas such as the SN

If the case of the former, the dog may have a shock type reaction and faint or collapse

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In these spectra, GABA is depleted more but the overall GABA level has a nonsignificant decrease in the PD group ( N = 38) compared to HC, ( N = 30) (with no statistical significance)

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