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This dual push-pull is why the IGF-1Akt axis is considered a master regulator of muscle mass, although its exact role in the adult muscle response to mechanical load is, by the authors own account, less clearly defined than its role in development and regeneration

This paper is based upon work supported by Science, Technology & Innovation Funding Authority (STDF) under grant number 46040

doi: 10.1016/j.scitotenv.2022.158689

In addition to inorganic Cu +/2+ , Copper oxide nanoparticles and organic forms of Cu +/2+ complexes could also be used to synthesize cytotoxic anticancer drugs, leading to irreversible membrane damage and cell death

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