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Description
Its intracellular concentration usually indicates oxidative cellular stress, as the latter profoundly affects the cellular thiol balance, usually causing a decrease in the cellular GSH/GSSG ratio

The ENO2 gene is located on chromosome 12p13.31 and is composed of 12 exons encoding a protein of 434 amino acids

NA: not available

doi: 10.2337/db16-0153

In a similar way, the administration of n- hexane and its metabolite 2, 5-hexanedione (400 mg/Kg/day/5 days a week/6 weeks, i.p.) to mice caused that both chemicals reduced the striatal dopamine concentration by 38 and 33%, respectively, but neuronal cell loss was not confirmed (Pezzoli et al., 1990)
