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CDP promoted melanogenesis by activating MAPK signaling pathway and up regulating the expression of MITF and its downstream genes Tyr, TRP1 and Trp2, including increasing the phosphorylation levels of p38, JNK and ERK proteins

When combined with ARA-290, a peptide specifically engineered to target inflammation and nerve regeneration, we see a potential "synergy" that could redefine how we look at healing

Macropinocytosis is a non-selective, actin driven process where the cell membrane folds outward to engulf surrounding fluid and particles into large vesicles inside the cell

A subject may be either a healthy human or a patient

doi: 10.1105/tpc.012500