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Description
Small changes in the time of administration relative to ischemia can shift PRPs effect from anti-apoptotic to apparently pro-inflammatory, as shown in models where PRP given before ischemia produced stronger protective outcomes than when applied at reperfusion 52

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J Periodontol 66(6):429437

10.1038/NPROT.2013.032 8 BrahadeeswaranS.ChitluriK

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